Abstract A notable class of problems often employed in undergraduate courses on differential equations
is that of mixing problems: those involving a number of brine-filled tanks equipped with a number of
brine-transporting pipes. Closed mixing problems, which feature neither filler nor drainer pipes, have
been studied on a general level, where the flow networks are represented by digraphs [A. Slav\'ı k,
Mixing problems with many tanks, American Mathematical Monthly, 120 (2013), 806-821]. In this
paper, we extend the study to open mixing problems, which may feature filler and/or drainer pipes,
representing the flow networks by a generalization of digraphs: quasi-digraphs. We formulate sufficient
conditions under which such a mixing problem can be modeled as a system of linear ordinary differential
equations whose coefficient matrix is the negative of the transpose of the Laplacian of the associated
quasi-digraph. Subsequently, we formulate the analogues for mixing problems represented by weighted
quasi-digraphs, and by cascade-type multilayer weighted quasi-digraphs. At the end of this paper, we
propose suggestions for instructors on how our materials could be distilled to form a set of taught
materials or a mini-project enriching an undergraduate differential equations course.
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